Mixed Agonist/Antagonist and Partial Agonist Opioid Analgesics The concomitant usage of opioids with other opioid analgesics, for instance butorphanol, nalbuphine, pentazocine, may well decrease the analgesic effect of oxycodone and acetaminophen tablets and/or precipitate withdrawal symptoms. Recommend patient to stay away from concomitant use of